"I'm so excited to be part of this ground-breaking franchise," says Roberts, who most recently appeared in "Valentine's Day" and can be seen in the upcoming Schumacher pic "Twelve." "It's the perfect opportunity for me to do something completely different than I've ever done before."
The "Scream" franchise has grossed over $500 million to date and helped revitalize the suburban horror genre in the late 90s.
Roberts joins a cast which already includes "Scream" vets Neve Campbell, Courtney Cox and David Arquette.
Dimension Films will release the horror sequel on April 15, 2011.